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Journal of Molecular Endocrinology , 8(3), 213223

The peptide demonstrates cytoprotective effects through modulation of cellular stress responses and appears to enhance collagen synthesis and extracellular matrix remodeling, which are fundamental processes in tissue repair and regeneration

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[195] elucidated that in the post-ischemic heart, when the eNOS cofactor tetrahydrobiopterin (BH4) is exhausted, its repletion only partially repaired eNOS-mediated coronary vasodilation, specifying additional critical elements that trigger endothelial dysfunction
