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Phase III trials were discontinued due to funding, not safety concerns

Special Dosing Considerations for Specific Populations When giving Vitamin B12 injections, its key to think about different patient groups

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(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)