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Orthop 57 (Suppl 1):105114

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For infection, U2OS cells were detached and resuspended to achieve ~ 25% confluency in a 384-well glass-bottom plate (Cellvis, cat# P384-1.5H-N)

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The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex

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Accordingly, pharmacological inhibition of SLC7A11 or cysteine deprivation blocks GSH synthesis, leads to GSH depletion, and induces ferroptosis by disabling the antioxidant defense system 85,137

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