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Organizations that treat Orange Book analysis as a research task to be delegated to paralegals or junior analysts, rather than a core strategic intelligence function, will consistently find themselves behind on LOE timelines, surprised by Paragraph IV challenges they could have anticipated, and unable to quantify the IP risk embedded in M&A targets at the speed that deal timelines require

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Step 6: Slowly depress the plunger until all the solution is injected, then withdraw the needle smoothly

Science 329 , 407 (2010)

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