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The recommended daily intake of B12 for adults is 2.4 mcg per day

doi: 10.1038/nbt.1630 26 BolgerAMLohseMUsadelB
Theranostics 10 (11), 51075119
Microbiome Metabolites and Thyroid Dysfunction

Elevated copper levels can also lead to a decrease in S-adenosylmethionine (SAMe) and glutathione levels, which can affect methylation and toxin removal from the body
