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This endocrine-like axis, linking adipose tissue, endothelial dysfunction, and atherosclerosis, may explain in part the ramifications of obesity-caused atherosclerosis

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Glutathione S-transferases (GSTs) are the enzymes expressed in the cytosol, microsomes, and mitochondria and catalyze glutathione conjugation to electrophilic compounds, not only produced from exogenous xenobiotics by biotransformation but also arise from endogenous substances

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