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If the cycle is stuck at this point, this leads to a lack of SAM, as well as to many other health problems due to the accumulation of homocysteine

Cancer 8 , 967975 (2008)

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81 Previous report entails the resistance of VM to anti-angiogenic inhibitors such as endostatin and TPN-470 in B16F10 murine melanoma model, as well as in melanoma tumor cells