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The lactylation of K62 on pyruvate kinase M2 (PKM2), a crucial enzyme in glycolysis, inhibits its transition from tetramer to dimer and enhances its pyruvate kinase activity, thereby suppressing inflammatory metabolic adaptation in pro-inflammatory macrophages

Antioxidant Protection: Glutathione neutralizes harmful free radicals, which are unstable molecules that contribute to cellular damage and accelerate aging

Rather, rapid metabolic effects must cause the stimulation of sulfur assimilation by photorespiratory conditions

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