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J Clin Diagn Res 7 (2), 278283 (2013) J.-J

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P., Tena-Solsona, M., Van Esch, J
NQO1 and HO-1 are phase II genes that scavenge reactive nitrogen species (RNS), reactive oxygen species (ROS), xenobiotics, and detoxify electrophiles and also retain cellular reducing capacity (Figure 1

As a result, vitamin B12 deficiency can show clinical effects such as progressive demyelination, peripheral neuropathy and haematological abnormalities (such as macrocytic anaemia and neutrophil hypersegmentation)
