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The affinity of the PV3 wild type was 51.0 nM, whereas the mutants K87pAcF, C23pAcF, S85pAcF and N77pAcF showed a significant increase in binding affinity

Syntheses and antitumor activities of N 1, N 3-dialkyl- N 1, N 3-di-(alkylcarbonothioyl) malonohydrazide: the discovery of elesclomol

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