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In this assay, the extracellular bacteria are killed by gentamicin, but the intracellular bacteria are shielded from the antibiotic because of the limited penetration of the gentamicin into eukaryotic cells

Rfpermute: Estimate Permutation P-Values for Random Forest Importance Metrics (2022)

Humans express two glutaredoxin encodeing genes, GLRX and GLRX2
Biofilms have been shown to protect HSV-1 from antivirals and UV laser treatment (Ascione et al., 2017), and biofilms can act as a reservoir of HSV-1 (Mazaheritehrani et al., 2014)

Given that polyamine synthesis is dependent upon methionine, MR may be a novel approach to inhibit cancer cell growth by downregulating polyamine formation
