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Description
189 Multiple tissue-derived tumor samples show a large number of Arg1-positive myeloid cells in the tumor microenvironment

Pharmaceuticals 15 , 1306 (2022)
While providing invaluable insights to the field of immuno-metabolism, the technical limitations of bulk cellular measurements often used to measure metabolic respiration by means of metabolite tracing and/or oxygen consumption (OCR) and extracellular flux analyses (ECAR), are not able to adequately capture the newly-appreciated phenotypic and functional and diversity associated with the heterogeneous nature of in vitro DC culture systems 22,23

10.1002/jcp.28631 106 MaleV.MoffettA

Using Connectivity Map data from the Broad Institute, researchers found that GHK modulates 4,000+ genes