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It is well known that during the oxidative stress caused by the exhaustive exercise, the levels of biochemical indices, e.g., lactate dehydrogenase (LDH) and superoxide dismutase (SOD) involved in the elimination of metabolites generated from fatigue, are significantly altered, ultimately alleviating the EIF, while the regulatory mechanisms underlying the involvement of LDH and SOD in the response to EIF are extensively explored (Armstrong et al., 1983
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Disruption of mitochondrial function may be responsible for a wide range of disorders involved in enterocyte dysfunction, including (a) enterocyte dysfunction following traumatic brain injury (93, 94)

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