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Protective Effect of the Combined use of L-carnitine and L-arginine against Hepatic Ischemia-Reperfusion Injury in Rats 213230

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88 When lactate is used as a marker for muscle damage in patients with mitochondrial disorders, CoQ10 seems to diminish the initial rise in lactate upon exercise and increases VO 2 max, although it failed to affect the total lactate level after exercise or improve overall exercise capacity in a 2010 randomized trial

This is important in tissues that rely heavily on fat as a fuel source, like skeletal muscle and the heart

TMAO is a metabolite produced by gut microbiota
