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[Abstract]2026 Jan 1;168(Pt 1):115768

As the process continues, dehydration and rearrangement leads to cross-links between adjacent proteins, resulting in protein aggregates, advanced glycation end products (AGE's) and increased oxidative stress (glycoxidation)

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184,185 Upregulated USP20 expression in oxaliplatin-resistant HCC cells is associated with poor prognosis, while genetic knockdown or pharmacological inhibition of USP20 can trigger ferroptosis and increase the sensitivity of HCC cells to oxaliplatin both in vitro and in vivo

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