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They're a secondary benefit tied to the metabolic component
doi: 10.1034/J.1399-3038.2002.00010.X 236 RosenlundHMagnussonJKullIHkanssonNWolkAPershagenGet al
Alprostadil: Enhances blood flow by expanding blood vessels
Non-genotoxic carcinogens do not cause direct DNA damage
