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AlphaFold predictions of complexes between NS3h, RNA and/or NS5B suggest that NS3h both remodels the cis-acting RNA elements and unwinds the terminal stem-loop of the HCV genome rendering the template accessible for de novo initiation of () strand synthesis by NS5B

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10.1007/s00439-015-1551-8 22 ShibataN.HasegawaY.YamadaK.KobayashiH.PurevsurenJ.YangY.et al (2018)

Hepatology 68 , 229A (2018)
