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It was recently shown that biallelic mutations in ADH5 and accumulation of FA can cause a particular type of IBMFS observed in individuals carrying the highly prevalent ALDH2*2 mutation (IBMFS/AMeD syndrome) 10, 14
doi: 10.1055/s-0033-1349333
Additionally, the provider can apply topical numbing cream to the injection area to minimize the discomfort
Moreover, three down-regulating proteins are directly involved in nodule process
