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T helper cells contribute to scar formation through the secretion of IL-4 and IL-13, while regulatory T cells exert an anti-inflammatory effect by producing IL-10 and prostaglandin E2, which inhibit fibrosis (Xu et al., 2024)

Each dataset was randomly partitioned into two subsets, where 2/3 were used for training and the remaining 1/3 for test

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Up to twelve mutational combinations were found to significantly increase peptide affinity for amylin receptor extracellular domains by over 100-fold