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The Hippo pathway As a central regulator of cell growth and size, it is not surprising that the Hippo pathway is involved in a number of tumour types, including NF2-associated tumours
In the Preiss-Handler pathway: nicotinic acid (NA) is converted into NAMN via the catalytic activity of NA phosphoribosyltransferase

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This could potentially indicate a shift towards cell survival and away from apoptosis