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CO exposure has been linked to impaired lung function, leading to reductions in FEV1 and forced vital capacity (FVC) regardless of exposure levels [103]
In addition, hypothemycin inhibits the phosphorylation of the mitogen-activated protein kinase kinase (MEK)3/6 substrate p38, the MEK4/7 substrate c-Jun N-terminal kinase (JNK), and the TGF--activated kinase 1 (TAK1) substrate IB kinase
It is characterized by progressive memory impairment and cognitive dysfunction
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