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This observation aligns with previous work showing that pharmacological inhibition or genetic ablation of NMDA receptors in agouti-related-protein (AgRP)-expressing neurons alters synaptic adaptation to fasting 39,40

[DOI] [PMC free article] [PubMed] [Google Scholar] 202.Zanoli L., Briet M., Empana J.P., Cunha P.G., Mki-Petj K.M., Protogerou A.D., Tedgui A., Touyz R.M., Schiffrin E.L., Spronck B., Bouchard P., Vlachopoulos C., Bruno R.M., Boutouyrie P., P.S.t.E.S.o.H.W.G.o.V.S Association for research into arterial structure, function, A

The resulting tryptic peptides were extracted by 5% formic acid/50% acetonitrile and concentrated using a SpeedVac (Thermo Scientific)

Mutations in several genes have been associated with monogenic forms of Parkinson's disease, including SNCA, LRRK2, Parkin, PINK1 , and DJ-1

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