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In regard to arginase inhibition, development of ARG2-specific inhibitors would help limit issues associated with disruption of the urea cycle in the liver, where ARG1 is more abundant

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Saudi Pharmaceut J 28:114 Karaman S, Ttem E, Bakan KS, Apak R (2009) Comparison of total antioxidant capacity and phenolic composition of some apple juices with combined HPLC-CUPRAC assay

( c ) Pie chart showing the fraction and ( d ) graph showing total numbers for stromal cell populations infected by MCMV:mCherry (TRCs, T cell zone reticular cells

This phenomenon is thought to be due to the inability of cells to restore normal GSH levels or to increased production of reactive oxygen species (ROS), which can damage macromolecules fundamental to cell survival before being deactivated by antioxidant defenses