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Functional GTP cyclohydrolase 1 exists as a homodecamer that consists of two tightly associated dimers that each comprise a pentameric complex of the GTP cyclohydrolase 1 monomers

Huo Z, Yu L, Yang J, Zhu Y, Bennett DA, Zhao J

This vasodilation response causes congestion, which increases pressure and pain receptor activation

A number of scientific papers have demonstrated that the KD lowers blood pressure [25,145] even more effectively than the DASH (Dietary Approaches to Stop Hypertension) diet, including a 2023 randomised controlled trial [194]
