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Leung, et al

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While tirzepatide does not directly target reproductive hormones, the significant weight loss and metabolic changes it produces can influence the hypothalamic-pituitary-ovarian axis that regulates menstruation

intralesional corticosteroid injection Hurley Stage II: First line: Add tetracycline to stage I regimen Second line: Tumor necrosis factor inhibitors (adalimumab, etanercept) Third line: Oral retinoid (acitretin), oral clindamycin and rifampin Refractory cases of Hurley stage I and II can be advanced to a further Hurley stage treatment paradigm

Brunet, A