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Description
When there is thiamine deficiency, the thiamine dependent enzyme alphaketoglutarate dehydrogenase (KGDH) will not be activated and will result in damage of the mitochondria and eventually cause cell death 4
Pomalyst is an oral medication that is taken along with dexamethasone
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Mol Cell 58:95109 Milligan L, Sayou C, Tuck A, Auchynnikava T, Reid JE, Alexander R, Alves FL, Allshire R, Spanos C, Rappsilber J et al (2017) RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit
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