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2021: An RCT of 76 women (average age 55) with obesity and knee osteoarthritis found 1 g/day L-carnitine for 12 weeks did NOT reduce pain, stiffness, or improve physical function versus placebo [3][52]
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Mitochondria, oxidative metabolism and cell death in stroke
These effects may be more pronounced in those with pre-existing conditions or caffeine sensitivity, increasing the risk of adverse cardiovascular events
Recent studies suggest that, for optimal outcomes, the use of antidepressants should be tailored to patient-specific comorbidities and symptoms
