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Additionally, liver metastasis can cause symptoms of liver dysfunction, such as jaundice, which manifests as yellowing of the skin and eyes due to extensive tumor invasion [106]

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These complexes bind to the ARE in gene promoters, triggering the expression of over 200 genes involved in cellular defense against oxidative stress and inflammation

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For example, myeloid cells that take on a foamy appearance are a key driver of the inflammatory response after an IS

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