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99 Additionally, molecular biophysics research examines the effects of various biochemical factors, such as hormones and growth factors, on muscle function and adaptation
Another nonclassical degradation inducer of the GPX4 protein is a missense mutation in the gene encoding its synthase and its pathogenic variant (the R152H variant), suggesting that Lys125/Lys127 are sites for ubiquitin ligation and subsequent degradation [69,70]

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Nash TP, Benedict SR