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E2 interacted with ER at the plasma membrane, activated PKA or MAPKs, phosphorylated CREB, modulated CRE-mediated TH transcription in PC 12 cells [106], and increased catecholamine synthesis in cultured bovine adrenal medullary cells [107,108]
GFAP and UCH-L1 discriminated excellently between good and poor neurological outcome at all time-points (AUROC GFAP 0.88-0.89

In shrimp, Vago-like peptides may play multiple roles in antiviral defense and can adopt functions as both signaling molecules and pathogen sensors (229)

To further evaluate this process within the electron distribution chain of SmTGR, the U597S variant was studied

Further work will be needed to detect the relationship between autophagy and aging
