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Arachidonate 15-lipoxygenase type B: Regulation, function, and its role in pathophysiology

Microglial pro-inflammatory polarization is further sustained by dysregulated potassium (KCNJ2) and calcium (TRPM2) channels, creating a vicious cycle of cytokine release and immune activation

Five patients discontinued treatment due to lack of efficacy or unwillingness to continue

Weng Y, Zhang S, Huang W, Xie X, Ma Z, Fan Q

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