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They actually saw that folks who are deficient in vitamin B12 have a shrinkage of their brain, meaning they're losing volume, they're losing brain cells, and folks who are not vitamin B12 deficient have larger brains, more brain cells

Gastroenterology 150 , 684695 (2015)

BMJ 2011;343:d5928

To overcome this, higher subcutaneous insulin doses are needed to maintain glycemic control, and this results in aggravated systemic hyperinsulinemia
Moreover, overexpressed serine threonine tyrosine kinase 1 (STYK1) upregulates GPX4, resulting in SW900 cells to be less sensitive to ferroptosis (Lai et al., 2019)
