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Heres what a U-shaped curve looks like (data points are invented for illustration purposes): Photo by Innerbody Research In this invented example, the intervention in question does its best job at reducing a negative biomarker at around 200mg, after which the effect tapers off and soon becomes almost nonexistent

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In particular, exosomes derived from HEK293 cells treated with interferon- (INF-) carry a higher amount of OCTN2 with respect to exosomes derived from untreated cells

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Dehghanpour F, Tabibnejad N, Fesahat F, Yazdinejad F, Talebi AR Evaluation of sperm protamine deficiency and apoptosis in infertile men with idiopathic teratozoospermia

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