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Description
-Synuclein in monomeric form takes part in synaptic signal transduction: it binds to F0/F1-ATP synthase and increases the ATP synthesis rate in mitochondria under physiological conditions (Ludtmann et al., 2016)
CD analysis of an extracted G-rich region (126 nt) confirmed K-dependent G4 folding (Fig
The mitochondrial electron transport chain (ETC) consists of five multi-subunit complexes including NADH-coenzyme Q (CoQ) reductase (NADH dehydrogenase, Complex I), succinate dehydrogenase (Complex II), coenzyme Q-cytochrome c reductase (Complex III), cytochrome C oxidase (Complex IV), and ATP synthase (Complex V) [3,10]

In summary, our results suggest that HSF-1 influences ER proteostasis through multiple mechanisms in C

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