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It has been described in publications that an analogue of this domain, AOD9604, can increase lipolytic sensitivity and affect the expression of receptors beta-3 adrenergic in adipose tissue, and increase fat oxidation and energy expenditure in animal models

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A 50% reduction in tumor volume compared with free anti-CTLA-4 indicates the potential of peptide-based nanoparticles to improve the clinical standard [140, 141]