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In the clinical management of ICF syndrome, current protocols largely rely on immunoglobulin replacement therapy coupled with prophylactic antibiotic interventions (91, 92)

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Bcuwe P, Slomianny C, Camus D, et al

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For instance, certain bacteria express enzymes like -glucuronidase, which can deconjugate estrogen metabolites, potentially influencing the local hormonal milieu
