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As the cell lines exhibit a similar chemosensitivity pattern to that observed in clinical practice, these differences in glutathione and detoxification enzyme levels may prove to be important indicators of intrinsic drug resistance often seen in patients with non-small cell lung cancer

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Second, establish baseline measurements for all relevant biomarkers before introducing either compound
The vector, pET 15b (Figure 1A-1), was constructed by inserting a flexible spacer sequence, a hexa-histadine tag and thrombin cleavable sequence (Figure 1B, top)

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