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Also, in another study, an author observed that OA-affected chondrocytes exposed to high glucose levels were unable to downregulate GLUT-1 , resulting in higher glucose accumulation inside the chondrocytes and the production of more ROS, which is deleterious to the ECM (136), which leads to mitochondrial dysfunction and cartilage degradation

[DOI] [PMC free article] [PubMed] [Google Scholar] Sternberg P, Jr, Davidson PC, Jones DP, Hagen TM, Reed RL, Drews-Botsch C

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In the intervening months, state and city officials began discussing the most affordable water option for Flint