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Cytokine concentrations were calculated based on standard curves established with known cytokine standards, with final concentrations expressed in pg/mL [69]

An animal study on a mice model reported that liver-targeted ALDH2 inhibition decreased heavy drinking without affecting moderate drinking, which could be a molecular basis for hepatic ALDH2 targeting/editing for the treatment of AUD [144]

Under resting conditions, ASC is S-glutathionylated (notably at Cys171), a modification that impairs ASC oligomerization and prevents spontaneous inflammasome formation 67

10.1038/s41398-023-02606-z Transl

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