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Where possible, avoid suddenly reducing the B 12 dose or injection frequency, as too rapid dose reduction may worsen symptoms or lead to symptom recurrence.26 Instead, gradually increase the interval between B 12 injections over the course of several months while monitoring symptoms

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The relative importance of desnutrin/ATGL in lipolysis is illustrated by studies of gene ablation and functional loss of the enzyme

There are two distinct mechanisms by which B12 is absorbed: 1) passive diffusion across the mucous membranes of the gastrointestinal tract (Figure 1)

Vitamin B12 is essential for the production of red blood cells, the maintenance of nerve cell function, and the normal metabolism of fats and carbohydrates