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doi: 10.1038/nm1272
Va subcutnea : cualquier zona con tejido adiposo (abdomen, muslo, deltoides)
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Celver JP, Lowe J, Kovoor A, Gurevich VV, Chavkin C: Threonine 180 is required for g-protein-coupled receptor kinase 3- and beta-arrestin 2-mediated desensitization of the mu-opioid receptor in xenopus oocytes
This possibility is reflected in its clinical plasma half-life, which in the first-in-human study was measured to 85104 hours when administered at a dosage of 250 mg/kg [224]
