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Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

Eventually, abundant ROS promote a series of oxidative stress reactions, such as lipid peroxidation and activation of proteases, which trigger the cell-death cascade

Nevertheless, this very action on a smaller scale may also help moderate the immune system response

When data from the two populations in the WHIMS estrogen-alone and estrogen plus progestin ancillary studies were pooled as planned in the WHIMS protocol, the reported overall relative risk for probable dementia was 1.76 (95 percent CI, 1.19-2.60)

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