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Your body uses glutathione to neutralize harmful free radicals, support liver detoxification, and strengthen immune function

Zinc dysregulation within the endolysosomal system also intersects with cancer biology: the alcohol-deterrent and emerging anticancer agent disulfiram disrupts endolysosomal structure and raises intraluminal zinc in breast cancer cells, implicating zinc dysregulation in its cytotoxicity and suggesting that extracellular zinc availability modulates its efficacy 169

A very recent study showed that the current minimum recommendations were not designed for optimal cognitive function or longevity as participants with B12 levels deemed adequate by todays medical standards showed clear signs of neurological impairment, while healthy older adults (averaging 71 years of age) who did not have dementia or mild cognitive impairment averaged B12 levels at 414.8 pmol/L, much higher than the recommended minimum level (68)

From these results it is emerging that, under increased ROS flux, the cell necessitates to efficiently extrude GSH in order to propagate the redox stimulus