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Severe anemia with hemoglobin below 8 may justify transfusion or hospitalization
This transcriptional memory is driven by epigenetic changes, including histone deacetylation (mediated by histone deacetylases, HDACs) and repressive histone methylation (H3K27 trimethylation) at inflammatory gene loci (Maleszewska et al., 2021)
94 Moreover, among age-related diseases, MPO levels are also elevated in elderly subjects with AD, showing that MPO might be an important molecular link between atherosclerosis and AD and probably a promising biomarker for the detection and risk stratification of AD patients
doi: 10.3390/ijms241411775
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