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Comparative Biochemistry & Physiology Part A Molecular & Integrative Physiology 170 , 3845 (2014)

doi: 10.2174/1570159x16666180302115032

(2013) reported lower 5-HT levels in the blood plasma of hypothyroid rats in comparison to controls (68)

Another randomized controlled trial involving 48 migraine patients found 4,000 IU (100 mcg) vitamin D3 daily for 24 weeks reduced migraine frequency compared with placebo (Gazerani 2019)

During the adaptive immune phase, the production of antigen-specific T cells in regional lymph nodes, followed by their migration to the ocular surface under stress, initiates a pathological cycle of immune responses