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In 2018, Chamberlains group synthesized the new cereblon modulator CC-220 (Iberdomide), from compound 141 , which when alkylated and subsequently cyclized to form the glutarimide ring, is capable of binding to cereblon with greater affinity than lenalidomide 211,212

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Breakfast: Cheesy Scramble with Spinach & Tomatoes Lunch: Chicken Wrap with Peanut Lime Sauce Dinner: Low-carb Egg Roll in a Bowl Snack one: Rice Cakes with Avocado & Tuna Snack two: Peanut Butter & Honey Protein Squares Daily total = 102g carbs Day 3 Planning ahead by making your Overnight Chia-misu breakfast or Protein Pot snacks earlier in the week is key to making a low-carb eating plan stick