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Alternatively, ROS cause irreversible cellular damage due to lipid peroxidation, oxidation of protein, inactivation of enzymes, DNA damage, and interact with other vital constituents of plant cells through their strong oxidative properties, which drastically alter plant morphological structures, becoming disadvantageous for survival and productivity

[DOI] [PubMed] [Google Scholar] 101.Han D., Hanawa N., Saberi B., Kaplowitz N

2004;62 Suppl 1:101-107

An overall picture is emerging in which the contribution of effector functions to nAb-mediated protection depends on the individual antibodyvirus combination, even for antibodies directed to the same viral protein

In the context of research on HAPH, systems biology can be utilized to map out hypoxic response networks, pinpoint key regulatory elements, and identify potential therapeutic targets