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These compounds are lethal and evoke profound neurobehavioral responses, especially DHBT-1 which cause irreversible inhibition of mitochondrial complex I [64]

Monosaccharides containing an aldehyde groupsuch as glucoseare well-known reducing agents, while those with a ketone groupsuch as fructosecan only exhibit antioxidant activity after undergoing tautomeric conversion from a ketone to an aldehyde

Prior to initiation the study, an informed consent was provided by horse's riders, as well as by the owners

It has been reported, that in addition to mitochondrial sites of ROS formation, several non-mitochondrial sites may be triggered following hyperglycemia