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doi: 10.1007/s00775-007-0297-8 31 JensenP-D

Apigenin, a major flavonoid in chamomile, can bind to GABA receptors and increase their activity, which increases neural inhibition and relaxation, which may explain its mood-enhancing effects

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MSU crystals detect exogenous purine stimulation by activating purinergic receptors, which initiates the Raf/MEK/ERK signaling cascade

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