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When leg pain includes sensations of pins and needles, unexplained weakness, or coordination issues, a neurological cause should be explored

Most high-dose participants reached normal liver fat levels

However, in human systems the outcome of boosting NAD+ is complex and likely involves numerous pathways, from enhanced activity of sirtuins (implicated in longevity and metabolic control) to improved DNA damage repair, all of which are areas of ongoing investigation
Ruff, D., et al

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